THE Penicillin co*cktail Recipe (2024)

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Honey ginger syrup and fresh lemon juice lighten blended Scotch for a fortifying, belly-warming Penicillin co*cktail with Islay Scotch floated on top.

The Penicillin co*cktail Recipe is one of my favorites from my co*cktails recipes.

this recipe

The Penicillin co*cktail

Honey, ginger, and belly-warming blended Scotch all combine in one harmonious, home-cure-inspired co*cktail known as the Penicillin.

Topped with a woodsmoke, medicinally-aromatic layer of Islay Scotch (pronounced eye-la), the Penicillin co*cktail might be the next drink you reach for on a rough day, over a hot toddy.

What’s in a Penicillin co*cktail?

The secret to making the perfect penicillin co*cktail is gently floating the very last ingredient—Islay Scotch.

This ingredient creates a medicinal-inspired layer of Scotch that’s the “spoonful” of medicine that’s “taken” before you get to the sweet and comforting honey ginger concoction beneath.

  • Blended Scotch
  • Lemon juice
  • Honey ginger syrup
  • Ice
  • Islay Scotch floated on top
THE Penicillin co*cktail Recipe (2)

Penicillin co*cktail History

The Penicillin co*cktail was invented in 2005 by Sam Ross, a bartender at the popular New York-based bar Milk & Honey. [1] [2]

But why is it named Penicillin co*cktail?

If you know about the drug penicillin, you know that it was discovered by Alexander Fleming and his student, Cecil George Paine, to be effective against bacterial infection.

The Penicillin co*cktail’s name indicates that it might have a kind of curative effect on those feeling ill.

Think of it this way: when some folks feel a cold coming on, they make a hot toddy drink to soothe their sore throats and warm their bellies.

Whereas some might make this Penicillin co*cktail…

  • as the honey ginger syrup is thought to be restorative and throat-soothing,
  • the Islay Scotch tastes and smells like medicine while warming your belly on a cold night,
  • and the lemon juice is packed with Vitamin C.

Meanwhile, Sam Ross created the Penicillin co*cktail as a twist on the Gold Rush co*cktail with Scotch.

THE Penicillin co*cktail Recipe (3)

How to Make a Penicillin co*cktail

To make a penicillin co*cktail, start by checking your bar cart or bar fridge—do you have honey ginger syrup or honey syrup available?

If you have honey syrup, pour ¾ oz into the rocks glass and muddle it with a few slices of fresh ginger—this will serve as your honey ginger syrup.

Next, add blended Scotch, lemon juice, and honey ginger syrup to a co*cktail shaker filled with ice.

Shake until well mixed.

Now, fill the rocks glass with ice. Then, pour the Penicillin co*cktail mixture over the ice.

THE Penicillin co*cktail Recipe (4)

Next, use a spoon to float the Islay Scotch over the co*cktail.

Do this by pouring the Islay Scotch gently over the back of the spoon—creating a floating layer of Islay on the Penicillin co*cktail.

THE Penicillin co*cktail Recipe (5)

Lastly, garnish with a stainless steel skewerwith candied ginger and a lemon peel.

Now, enjoy the unique Penicillin co*cktail!

THE Penicillin co*cktail Recipe (6)

More co*cktails We Love

  • How to Make a Greyhound Drink
  • Cadillac Margarita
  • French Gimlet or the originalGimlet co*cktail Recipe
  • Dirty Martini
  • Coffee Martini
  • Bee’s Knees co*cktail

Thank you!

Thank you so much for stopping by and enjoying another co*cktail recipe adventure with me. Make this Penicillin co*cktail, then share a pic on Instagram or Facebook, tagging me at @beamingbaker and #beamingbaker. I can’t wait!

‘Til our next shaken, not stirred adventure…

Sending you all my love and maybe even a dove, xo Demeter ❤️

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THE Penicillin co*cktail Recipe (7)

THE Penicillin co*cktail Recipe

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  • Author: Demeter | Beaming Baker
  • Total Time: 2 minutes
  • Yield: 1 co*cktail 1x
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Description

Honey ginger syrup and fresh lemon juice lighten blended Scotch for a fortifying, belly-warming Penicillin co*cktail with Islay Scotch floated.

Ingredients

Scale

co*cktail

  • 2 oz blended Scotch
  • ¾ oz fresh-squeezed lemon juice
  • ¾ ounce honey ginger syrup* or
    • ¾ ounce honey syrup*
    • 3 slices fresh ginger*
  • Ice
  • ¼ oz Islay Scotch

Garnish

  • Candied ginger
  • Lemon peel

Instructions

  1. Add blended Scotch, lemon juice, and honey ginger syrup to a co*cktail shaker filled with ice. Shake until very well mixed and chilled.
  2. Strain into a rocks glass filled with ice.
  3. Pour Islay Scotch over the back of a spoon onto the co*cktail to float it.
  4. Garnish with candied ginger and a lemon peel or lemon wedge.

Notes

*If you only have honey syrup, muddle the ginger into your rocks glass. Then, follow the rest of the recipe as instructed.

  • Prep Time: 2 minutes
  • Cook Time: 0 minutes
  • Category: Drinks, co*cktails
  • Method: No Cook, Chill

More Drink Recipes

  • To quench your thirst…Cucumber Mint Water
  • Gibson Drink
  • Extra Dirty Martini
  • Irish Mule Recipe

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THE Penicillin co*cktail Recipe (2024)

FAQs

What is the story behind the penicillin co*cktail? ›

It was created in the early 2000s by Sam Ross, a bartender who worked at the pioneering New York co*cktail spot Milk & Honey. Ross took the elements of the Gold Rush co*cktail (bourbon, lemon, and honey), made it with blended Scotch, then added equal parts honey syrup and sweetened ginger juice.

What is Penicillin drink made of? ›

MADE WITH MAKER'S MARK®

A bit like a “cold toddy,” the Penicillin co*cktail brings together the comforting flavors of lemon and honey, a touch of smoke from scotch, a zing of ginger and, of course, Maker's Mark®.

What are the ingredients in Penicillin? ›

It is made up of an enclosed dipeptide formed by the condensation of L-cysteine and D-valine. This results in the formations of β-lactam and thiazolidinic rings. The key structural feature of the penicillins is the four-membered β-lactam ring; this structural moiety is essential for penicillin's antibacterial activity.

What is the difference between gold rush and Penicillin co*cktails? ›

While the Gold Rush was essentially a whiskey sour with honey, the Penicillin elevated this template with additional intricacies and a more elaborate flavour profile. Sam Ross concocted the Penicillin co*cktail in the mid-2000s while tending bar at the renowned Milk & Honey in New York City.

Why penicillin was banned? ›

The committee recommended that all antibiotics which are important in human medicine should be banned as growth promoters in farming. As a result, in the early 1970s the use of penicillin and tetracyclines were banned as growth promoters. An EU ban on all remaining antibiotic growth promoters was implemented in 2006.

Why did doctors stop using penicillin? ›

Almost from the beginning, doctors noted that in some cases, penicillin was not useful against certain strains of Staphylococcus aureus (bacteria that causes skin infections). Since then, this problem of resistance has grown worse, involving other bacteria and antibiotics.

What alcohol can you drink on penicillin? ›

Yes, you can drink alcohol with phenoxymethylpenicillin. Is there any food or drink I need to avoid? You can eat and drink normally while taking phenoxymethylpenicillin.

Why can't you drink on penicillin? ›

Antibiotics and alcohol can cause some of the same side effects. These include stomach upset, dizziness and drowsiness. Mixing antibiotics and alcohol can make these side effects worse.

Which drug is a natural penicillin? ›

Penicillin G and penicillin V (also known as penicillin V potassium) are natural penicillins. Providers use natural penicillins to treat a range of infections, including strep throat, syphilis and Lyme disease. Penicillin G comes in IV form. Penicillin V you can take by mouth.

What is the closest drug to penicillin? ›

Cephalosporins — Cephalosporins are a class of antibiotics closely related to penicillin.

How do you make penicillin? ›

How did they make penicillin?
  1. Penicillium mold naturally produces the antibiotic penicillin.
  2. Scientists learned to grow Penicillium mold in deep fermentation tanks by adding a kind of sugar and other ingredients. ...
  3. Then, scientists separated the penicillin product from the mold.

Why is penicillin not used today? ›

It is a well-researched antibiotic with few side effects. However, the overuse of penicillin and other antibiotics has driven some strains of bacteria to develop resistance to these drugs, making bacterial infections more difficult, and sometimes impossible, to treat.

What is the Queen's favorite co*cktail? ›

The Queen's Favorite co*cktail: The Dubonnet and Gin

Hidden among these rumors is the widely accepted fact that Queen Elizabeth's favorite co*cktail is a Dubonnet and Gin co*cktail. She enjoys one every day before dinner, among the three other drinks she supposedly consumes on a daily basis.

Why is it called a penicillin co*cktail? ›

Its name derives from the drug penicillin, discovered by Scottish scientist Alexander Fleming, hinting to the medicinal properties of some of its ingredients, with suggested effects similar to that of a hot toddy which is said to relieve the symptoms of cold and flu. It was first served in 2005 at Milk & Honey.

What is the strongest alcoholic co*cktail? ›

While Hemingway suggests drinking “three to five of these slowly”, we would definitely have to disagree. And last on our list, but certainly not the least (amount of alcohol, that is), we have the Aunt Roberta. This co*cktail contains 100% liquor and is widely regarded as THE strongest co*cktail in the world.

What is the story behind the discovery of penicillin? ›

In 1928 Dr Alexander Fleming returned from a holiday to find mould growing on a Petri dish of Staphylococcus bacteria. He noticed the mould seemed to be preventing the bacteria around it from growing. He soon identified that the mould produced a self-defence chemical that could kill bacteria.

What is the story of the penicillin miracle? ›

Florey's coat: the story of the penicillin miracle is an account of the discovery of penicillin by Nobel laureate Alexander Fleming in 1928 and the production of the β-lactam antibiotic by Norman Heatley and Fleming's fellow laureates Howard Florey and Ernst Chain at the Sir William Dunn School of Pathology at Oxford ...

What major disease did penicillin cure? ›

Today, penicillin, considered the first wonder drug, is used to treat throat infections, meningitis, syphilis and other bacterial infections. It works by inhibiting enzymes involved in building bacterial cell walls and by activating other enzymes that break these protective barriers down.

What was the main idea of discovering penicillin? ›

Alexander Fleming's Discovery

After isolating the mold and identifying it as belonging to the Penicillium genus, Fleming obtained an extract from the mold, naming its active agent penicillin. He determined that penicillin had an antibacterial effect on staphylococci and other gram-positive pathogens.

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